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LOCALIZED UNILATERAL HYPERHIDROSIS—A CLINICAL AND LABORATORY STUDY
Author(s) -
CUNLIFFE W. J.,
JOHNSON C. E.,
WILLIAMSON D. M.
Publication year - 1972
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1972.tb05050.x
Subject(s) - newcastle upon tyne , medicine , dermatology , art history , art
Summary.— Three case of unilateral idiopathic hyperhidrosis are described. Two of the lesions were congenital; the thrid occurred in later life. Quantitative sweat collections demonstrated that the sweat glands in the lesion were hyperresponsive to those stimuli, which normally evoked sweating in the skin sites where the lesions occurred. Hyper‐responsiveness of the sweat glands to cholinergic stimuli was also demonstrated, and histology revealed greatly enalrged glands. These results suggest that the hyperhidrosis is due to Increased glandular mass, although sweat gland hypersensitivity could notberuled out as an additional contributing factor to the hyperhidrosis. Local anticholinergic therapy was found to besuccessful in the treatment of all 3 patients.