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AN EXPERIMENTAL INVESTIGATION ON THE SITE OF SKIN DAMAGE INDUCING THE KOEBNER REACTION IN PSORIASIS
Author(s) -
STANKLER L.
Publication year - 1969
Publication title -
british journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.304
H-Index - 179
eISSN - 1365-2133
pISSN - 0007-0963
DOI - 10.1111/j.1365-2133.1969.tb16029.x
Subject(s) - psoriasis , dermatology , medicine
SUMMARY.— The mechanism by which the Koebner reaction could be provoked was studied in 6 patients with active psoriasis. It was concluded that purely epidermal or purely dermal damage was ineffective but that damage of the basement membrane was not essential. The factors determining a successful reaction are not clear. Injury of both epidermis and dermis appears to be essential but it is perhaps the degree of tissue damage which is important.