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Absorption of enteric and non‐enteric coated prednisolone tablets.
Author(s) -
Hulme B,
James VH,
Rault R
Publication year - 1975
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1975.tb02777.x
Subject(s) - enteric coated , enteric fever , enteric coating , prednisolone , absorption (acoustics) , enteric virus , medicine , chemistry , materials science , pharmacology , gastroenterology , virology , dosage form , typhoid fever , composite material
1. Relative rates of absorption of enteric and non‐enteric preparations of prednisolone were measured in five renal transplant recipients. 2. The absorption of the enteric coated preparation is delayed and the peak plasma concentration is much lower than that attained using the same dose of the uncoated material. 3. The therapeutic implications of these observations are discussed.