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Mapping rainbow trout immune genes involved in inflammation reveals conserved blocks of immune genes in teleosts
Author(s) -
Phillips R. B.,
Ventura A. B.,
DeKoning J. J.,
Nichols K. M.
Publication year - 2013
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/j.1365-2052.2011.02314.x
Subject(s) - biology , gene , rainbow trout , genetics , immune system , infectious hematopoietic necrosis virus , candidate gene , genome , synteny , fishery , fish <actinopterygii>
Summary We report the genetic map location of 14 genes involved in the inflammatory response to salmonid bacterial and viral pathogens, which brings the total number of immune genes mapped in rainbow trout ( RT , O ncorhynchus mykiss ) to 61. These genes were mapped as candidate genes that may be involved in resistance to bacterial kidney disease, as well as candidates for known QTL for resistance to infectious hematopoietic necrosis virus, infectious pancreatic necrosis virus and C eratomyxa shasta . These QTL map to one or more of the linkage groups containing immune genes. The combined analysis of these linkage results and those of previously mapped immune genes in RT shows that many immune genes are found in syntenic blocks of genes that have been retained in teleosts despite species divergence and genome duplication events.