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In vitro evaluation of the CeVOX TM continuous central venous oxygenation monitoring system *
Author(s) -
Baulig W.,
Dullenkopf A.,
Hasenclever P.,
Schmid E. R.,
Weiss M.
Publication year - 2008
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.2007.05376.x
Subject(s) - medicine , oxygen , saturation (graph theory) , oxygenation , limits of agreement , oxygen saturation , pulse oximetry , anesthesia , venous blood , reference values , analytical chemistry (journal) , nuclear medicine , chromatography , chemistry , mathematics , organic chemistry , combinatorics
Summary We investigated the in vitro performance of the CeVOX TM system for continuous monitoring of central venous oxygen saturation by spectrophotometry (Pulsion Medical Systems, Munich, Germany). Oxygen inflow into the system was varied, and oxygen saturation values measured by CeVOX were documented. Blood samples were simultaneously taken to assess oxygen saturation by co‐oximetry, and values were compared by Bland–Altman analysis. Sixty‐six data pairs were obtained at CeVOX and co‐oximetry values of 16–99% and 5.5–100%, respectively. Overall, CeVOX values only slightly overestimated co‐oximetry values (mean bias + 2.4%), but limits of agreement (2 SD of bias) were wide (− 11.8 to + 16.6%). Saturation measured by CeVOX underestimated that measured by co‐oximetry at higher oxygen concentrations and overestimated it at lower oxygen concentrations. There was a nearly linear correlation of the mean bias, suggesting a systematic error. We conclude that the current version of the CeVOX system does not reliably reflect oxygen saturation.