Premium
Economy in the use of muscle relaxants Vecuronium after pancuronium
Author(s) -
KAY B.,
CHESTNUT R. J.,
SUM PING J. S. T.,
HEALY T. E. J.
Publication year - 1987
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1987.tb03039.x
Subject(s) - medicine , muscle relaxant , anesthesia , pancuronium bromide , muscle relaxation
Summary Vecuronium is an intermediate duration, non‐depolarising muscle relaxant. When used during prolonged procedures, it may be given by intermittent injection, by continuous infusion or by a single very large dose at the start of anaesthesia. It may also be used to maintain relaxation after the initial use of a long‐acting agent, such as pancuronium. This study demonstrates that the effect of a dose of vecuronium used in this fashion is increased when interaction with pancuronium takes place. The clinical and theoretical implications of this observation are discussed.