Characterization of MLS b  resistance among  Staphylococcus aureus  and  Staphylococcus epidermidis  isolates carrying different SCC mec  types | Zendy

Teodoro Cristiane R. S. | Zendy; Mattos Cláudio S. | Zendy; Cavalcante Fernanda S. | Zendy; Pereira Eliezer M. | Zendy; Santos Kátia R. N. dos | Zendy

Premium

Characterization of MLS b resistance among Staphylococcus aureus and Staphylococcus epidermidis isolates carrying different SCC mec types

Author(s) -

Teodoro Cristiane R. S.,

Mattos Cláudio S.,

Cavalcante Fernanda S.,

Pereira Eliezer M.,

Santos Kátia R. N. dos

Publication year - 2012

Publication title -

microbiology and immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.664

H-Index - 70

eISSN - 1348-0421

pISSN - 0385-5600

DOI - 10.1111/j.1348-0421.2012.00481.x

Subject(s) - microbiology and biotechnology , sccmec , staphylococcus epidermidis , staphylococcus aureus , biology , clindamycin , erythromycin , methicillin resistant staphylococcus aureus , antibiotics , bacteria , genetics

This work characterizes MLS b resistance in 39 methicillin‐resistant Staphylococcus aureus (MRSA) and 32 Staphylococcus epidermidis (MRSE) isolates. Of 21 erm (A) gene encoding MRSA isolates, 71.4% carried SCC mec III, whereas of 12 isolates carrying the erm (C) gene, 83.3% carried SCC mec IV. Among the 25 MRSE isolates positive for the erm (C) gene, 80% had SCC mec IV or nontypeable cassettes. Isolates carrying these genes had MIC 90 ≥ 256 μg/mL to erythromycin and clindamycin. The msr (A) gene was associated with a low MIC 90 to these drugs. The erm (A) gene was associated with SCC mec III in MRSA isolates, whereas the erm (C) gene was associated with SCC mec IV in both MRSA and MRSE isolates.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research