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Isolation of Orientia tsutsugamushi from Patients in Shikoku and Finding of a Strain Which Grows Preferentially at Low Temperatures
Author(s) -
Tamura Akira,
Makisaka Yukie,
Enatsu Teruyuki,
Urakami Hiroshi,
Okubo Koji,
Fukuhara Masahiro,
Mahara Fumihiko
Publication year - 1999
Publication title -
microbiology and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.664
H-Index - 70
eISSN - 1348-0421
pISSN - 0385-5600
DOI - 10.1111/j.1348-0421.1999.tb03359.x
Subject(s) - orientia tsutsugamushi , okazaki fragments , strain (injury) , biology , scrub typhus , rickettsiosis , isolation (microbiology) , microbiology and biotechnology , rickettsiaceae , virology , rickettsiales , monoclonal antibody , antibody , bacteria , rickettsia , immunology , genetics , immunohistochemistry , virus , anatomy , proliferating cell nuclear antigen , eukaryotic dna replication
Abstract Three strains of Orientia tsutsugamushi were isolated from patients in Anan City, Tokushima Prefecture. The strains were identified as Karp type by analyses of reactivities with type‐specific monoclonal antibodies. One strain, Okazaki, was isolated in L cells cultivated at 31 C, but not in cells at 36 C or in mice. This strain showed better growth at 31 C than 36 C. This is the first report of an O. tsutsugamushi strain which grows preferentially at low temperatures.