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Case of localized scleroderma associated with osteomyelitis
Author(s) -
MUROI Eiji,
OGAWA Fumihide,
YAMAOKA Toshifumi,
SUEYOSHI Fumiko,
SATO Shinichi
Publication year - 2010
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2009.00751.x
Subject(s) - medicine , scleroderma (fungus) , magnetic resonance imaging , bone marrow , biopsy , osteomyelitis , pathology , inflammation , skin biopsy , radiology , surgery , inoculation
We report a 4‐year‐old girl presenting with progressive linear scleroderma affecting the right leg. Biopsy specimen disclosed typical histopathological findings of localized scleroderma. Right leg magnetic resonance imaging (MRI) showed high signal areas on T 2 ‐weighted images on the subcutaneous fatty tissue, muscles and bone marrow, suggesting that skin inflammation extended to the bone marrow. Oral corticosteroid therapy was instituted with improvement of both skin sclerosis and MRI findings. Our observations suggest that MRI examination should be considered in patients with localized scleroderma to evaluate the extension of the inflammation.