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Leukemia cutis in a patient with acute monocytic leukemia presenting as unique facial erythema
Author(s) -
HATTORI Tomoyasu,
AMANO Hiroo,
NAGAI Yayoi,
ISHIKAWA Osamu
Publication year - 2008
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2008.00542.x
Subject(s) - acute monocytic leukemia , medicine , erythema , leukemia cutis , dermatology , leukemia , pathology , monocytic leukemia , dermis , infiltration (hvac) , acute leukemia , physical examination , bone marrow , immunology , radiology , physics , thermodynamics
A 67‐year‐old woman was referred to our department with a 1‐month history of facial exanthemas. She had been diagnosed as having acute monocytic leukemia (French–American–British classification, M5b) based on the histological findings of bone marrow. Physical examination revealed diffuse edematous erythema on her cheeks, eyelids and glabella with scattered reddish papules. Histological examination demonstrated dense infiltration of atypical mononuclear cells in the dermis. Specific cutaneous lesions could occur in acute monocytic leukemia more frequently than in other types of leukemia, but rarely show symmetrical edematous erythema limited to the face.