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Paraneoplastic pemphigus presenting as erythrodermic lichenoid dermatitis with concomitant features of pemphigus foliaceus
Author(s) -
FUKUMOTO Takaya,
SHIROYAMA Yoshimi,
NIIZEKI Hironori,
KOBAYASHI Nobuhiko,
ASADA Hideo,
ISHII Norito,
HASHIMOTO Takashi,
MIYAGAWA Sachiko
Publication year - 2007
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2007.00347.x
Subject(s) - pemphigus foliaceus , desmoglein 1 , paraneoplastic pemphigus , dermatology , medicine , pemphigus , autoantibody , desmoglein 3 , erythroderma , desmoglein , pemphigus vulgaris , antibody , immunology
We describe a patient with paraneoplastic pemphigus who presented with erythrodermic lichenoid dermatitis, later developing blisters of pemphigus foliaceus type and oral erosive lesions. In addition to antibodies against the plakin family proteins, the patient's serum was positive for anti‐desmoglein 1 antibodies without coexisting anti‐desmoglein 3 activities by enzyme‐linked immunosorbent assay, which is a very rare autoantibody profile in paraneoplastic pemphigus.