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Stimulation of the renin‐angiotensin system and drinking by papaverine in the seawater eel, Anguilla anguilla
Author(s) -
Tierney M. L.,
Cramb G.,
Hazon N.
Publication year - 1995
Publication title -
journal of fish biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.672
H-Index - 115
eISSN - 1095-8649
pISSN - 0022-1112
DOI - 10.1111/j.1095-8649.1995.tb01107.x
Subject(s) - papaverine , captopril , renin–angiotensin system , medicine , angiotensin ii , endocrinology , biology , stimulation , vasoactive , plasma renin activity , blood pressure
The administration of papaverine (a hypotensive agent) caused an elevation in plasma angiotensin II concentration in the seawater eel, with a corresponding increase in drinking rate. Captopril completely abolished papaverine‐induced increase in drinking and reduced papaverine‐stimulated plasma angiotensin II concentrations by over 80%.