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Dendritic cells, DRiPs, and DALIS in the control of antigen processing
Author(s) -
Pierre Philippe
Publication year - 2005
Publication title -
immunological reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.839
H-Index - 223
eISSN - 1600-065X
pISSN - 0105-2896
DOI - 10.1111/j.0105-2896.2005.00300.x
Subject(s) - antigen presentation , major histocompatibility complex , biology , antigen processing , immune system , immunology , antigen , cross presentation , dendritic cell , antigen presenting cell , neuroscience , microbiology and biotechnology , t cell
Summary: The study of the cell biology of antigen processing and presentation has greatly contributed to our understanding of the immune response. The work of many immunologically inclined cell biologists has also permitted new insights into cellular mechanisms shared by many cell types. Here are described recent and particularly exciting findings on the regulation of major histocompatibility complex class I‐restricted presentation in dendritic cells and their contribution to the deciphering of the cellular response to pathogen detection.