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Ozone and SIRT 3: an unexplored paradigm
Author(s) -
Syed Deeba N.,
Mukhtar Hasan
Publication year - 2013
Publication title -
experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.108
H-Index - 96
eISSN - 1600-0625
pISSN - 0906-6705
DOI - 10.1111/exd.12143
Subject(s) - oxidative stress , ozone , skin aging , chemistry , microbiology and biotechnology , biology , medicine , biochemistry , dermatology , organic chemistry
Abstract Exposure to environmentally relevant doses of ozone induces oxidative stress and is associated with adverse effects at tissue level. Delineating the role of sirtuin3, involved in cellular energy homoeostasis, in the response of skin to ozone can be a step towards developing prevention strategies against cutaneous pathologies.