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A large scale prospective clinical and psychometric validation of the EORTC colorectal ( QLQ ‐ CR 29) module in Polish patients with colorectal cancer
Author(s) -
Sanna B.,
Bereza K.,
Paradowska D.,
Kucharska E.,
Tomaszewska I.M.,
Dudkiewicz Z.,
Golec J.,
Bottomley A.,
Tomaszewski K.A.
Publication year - 2017
Publication title -
european journal of cancer care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 67
eISSN - 1365-2354
pISSN - 0961-5423
DOI - 10.1111/ecc.12713
Subject(s) - medicine , colorectal cancer , prospective cohort study , scale (ratio) , cancer , oncology , general surgery , physics , quantum mechanics
The purpose of our study was to assess if the Polish translation of the European Organisation for Research and Treatment of Cancer ( EORTC ) Colorectal Cancer (CRC)‐Specific Quality of Life Questionnaire ( QLQ ‐ CR 29) is an acceptable and psychometrically valid measure to collect quality of life (QoL) data in Polish patients with CRC for use in clinical trials and clinical practice. A total of 150 patients undergoing treatment for CRC were prospectively enrolled in the study. Psychometric assessment of the translated QLQ ‐ CR 29 structure, reliability, convergent and divergent validity, and clinical validity was subsequently performed. The Cronbach's alpha coefficient ranged from 0.70–0.89, indicating acceptable internal consistency. For test–retest reliability, the ICC s for each item ranged from 0.59–0.91, with exceptions for urinary incontinence and dysuria, indicating good to excellent reproducibility. In multi‐trait scaling analyses, the criterion for item convergent and divergent validity was satisfied. The correlations between the EORTC QLQ ‐ CR 29 and QLQ ‐C30 scales were mostly low ( r < .40), with a few items demonstrating higher correlations. The known group comparisons analyses demonstrated the ability of the questionnaire to distinguish between patients’ differing age, stoma status, and treatment intent. The Polish translation of the QLQ ‐ CR 29 is a psychometrically reliable and valid tool. The results of this study are congruent with that of EORTC validation.