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Sildenafil‐induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms: Case report with review
Author(s) -
Gupta Sunil K.,
Sushantika Sushantika,
Abdelmaksoud Ayman
Publication year - 2020
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1111/dth.13826
Subject(s) - sildenafil , medicine , erectile dysfunction , drug , cgmp specific phosphodiesterase type 5 , adverse effect , medical prescription , eosinophilia , dermatology , adverse drug reaction , pharmacology
Abstract Sildenafil is one of the commonest over the counter drugs which is orally taken by the people for sexual enhancement. It is an inhibitor of phosphodiesterase type 5 (PDE5) and results in engorgement of carpora cavernosa and help in erectile dysfunction. There are fewer adverse cutaneous drug reactions reported by sildenafil perhaps due to use of the drug without medical prescription. Here we are reporting a case of sildenafil induced hypersensitivity syndrome that is possibly the first one and reviewing the medical literature on type of adverse cutaneous drug eruption due to sildenafil and other PDE5 inhibitors.