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Higher protein diet for weight management in young overweight women: a 12‐month randomized controlled trial
Author(s) -
Griffin H. J.,
Cheng H. L.,
O'Connor H. T.,
Rooney K. B.,
Petocz P.,
Steinbeck K. S.
Publication year - 2013
Publication title -
diabetes, obesity and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.445
H-Index - 128
eISSN - 1463-1326
pISSN - 1462-8902
DOI - 10.1111/dom.12056
Subject(s) - weight loss , overweight , medicine , randomized controlled trial , body mass index , weight management , carbohydrate , zoology , obesity , statistical significance , body weight , gastroenterology , endocrinology , biology
Clinical research on weight management in young women is limited. This randomized controlled trial compared the efficacy of two iso‐energetically restricted (5600 kJ ) diets [higher protein ( HP ): 32% protein, 41% carbohydrate, 25% fat or higher carbohydrate ( HC ): 20, 58, 21%, respectively] in 71 ( HP : n = 36; HC : n = 35) young healthy women (18–25 years; body mass index ≥ 27.5 kg/m 2 ) for weight (kg; percent weight loss), body composition, metabolic and iron changes assessed at baseline, 6 and 12 months. Data: mean (95% CI ). In HP completers at 6 months, percent weight loss was higher [ HP : 9.3 (5.6–13.1); HC : 5.1 (2.3–7.9)%; p = 0.06]; although, this did not reach statistical significance. Absolute weight [ HP : 8.9 (5.3–12.5); HC : 4.6 (2.2–7.0) kg; p = 0.034] and fat loss [ HP : 8.0 (4.4–11.5); HC : 3.4 (1.3–5.6) kg; p = 0.022] were significantly greater. No significant between‐diet differences were observed at 12 months. Biochemistry remained within normal ranges with HP showing superior preservation of ferritin at 6 months [ HP : 53 (40–66); HC : 46 (30–61) µg/l; p = 0.029]. Both diets supported clinically meaningful weight loss with HP tending to be more effective in the medium‐term.