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Effects of oxidized fish oil intake on tissue lipid metabolism and fatty acid composition of channel catfish ( I ctalurus punctatus )
Author(s) -
Dong Guifang,
Zhu Xiaoming,
Ren Hongxiang,
Nie Boyao,
Chen Lu,
Li Hui,
Yan Bo
Publication year - 2014
Publication title -
aquaculture research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.646
H-Index - 89
eISSN - 1365-2109
pISSN - 1355-557X
DOI - 10.1111/are.12138
Subject(s) - catfish , fish oil , lipid metabolism , food science , biology , ictalurus , polyunsaturated fatty acid , metabolism , fatty acid , lipase , biochemistry , enzyme , fish <actinopterygii> , fishery
Abstract Recent studies in terrestrial animals have shown that feeding the oxidized lipids led to a reduction in triacylglycerols ( TAG ) and total cholesterol ( TC ) in liver and plasma. However, limited information is available on the effect of oxidized lipids on lipid metabolism in fish. In this study, four diets containing 0 g kg −1 (control: fresh fish oil), 30 g kg −1 (low‐oxidized oil, LOO ), 60 g kg −1 (medium‐oxidized oil, MOO ) and 90 g kg −1 (high‐oxidized oil, HOO ) graded oxidized oil levels with the same dietary lipid level were fed to channel catfish for 86 days. The tissue lipid metabolism and fatty acid composition of the fish were investigated after this period. The results showed that plasma and liver concentrations of TAG and TC decreased with increasing dietary oxidized oil level ( P < 0.05). Decreasing liver lipoprotein lipase and hepatic lipase activities were observed with increasing dietary oxidized fish oil inclusion ( P < 0.05). The liver C22:6n−3 concentrations significantly decreased with increasing dietary oxidized oil level ( P < 0.05), while muscle lipid had a high proportion of polyunsaturated fatty acids. It suggests that the adverse effects of dietary oxidized oil may be induced by inhibiting lipid metabolism enzymes and, consequently, inhibition of cholesterol homoeostasis and fatty acid synthesis.