Autologous serum and plasma rich in growth factors in ophthalmology: preclinical and clinical studies
Author(s) -
Anitua Eduardo,
Muruzabal Francisco,
Tayebba Ali,
Riestra Ana,
Perez Victor L.,
MerayoLloves Jesus,
Orive Gorka
Publication year - 2015
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/aos.12710
Subject(s) - medicine , platelet rich plasma , autologous blood , regenerative medicine , intensive care medicine , ophthalmology , immunology , surgery , stem cell , platelet , biology , genetics
Abstract The use of blood derivatives represents an alternative therapeutic approach that is gaining interest in regenerative medicine due to its potential to stimulate and accelerate tissue healing. Autologous serum eye drops and platelet‐enriched plasma eye drops are being used in the treatment of different ophthalmological disorders. In this review, we summarize the different blood‐derived formulations used in the treatment and care of ocular surface disorders. The biological basis and use of autologous serum and plasma rich in growth factors are deeply evaluated as well as the challenges to be addressed in the future in this new generation of blood‐derived therapies.