Long‐term outcomes following laparoscopic anterior and Nissen fundoplication

Background Limited evidence exists to which operation gives best long‐term outcomes for gastro‐oesophageal reflux disease. This study aimed to assess long‐term symptomatic outcome and satisfaction following laparoscopic anterior ( LA ) or Nissen fundoplication in a specialist upper gastrointestinal unit. Methods Patients who underwent primary LA or Nissen ( LN ) fundoplication between May 1994 and June 2010 were identified from a prospectively collected database. DeMeester, modified DeMeester, ‘Gastrointestinal Symptom Rating Scale’ scores and patient satisfaction were assessed by questionnaire. Results A total of 387 patients underwent surgery and 246 patients (65%) completed questionnaires, with 181 LA patients and 65 LN patients. Median follow‐up was 83 months for LA and 179 months for LN ( P < 0.001). A total of 218/245 (89%) reported major improvement in symptoms and 27 (11%) reported poor outcomes. There was no differences between LA and LN for symptom scores at short (<5 years) or long‐term follow‐up (>5 years). Women reported significantly higher DeMeester scores and lower satisfaction ( P = 0.012). One hundred and eighteen (48%) patients were taking proton pump inhibitors ( PPI ) at follow‐up despite high satisfaction rates. Conclusion LA and LN have similar long‐term results with patients reporting high satisfaction levels. Women reported more symptoms and less satisfaction than men. Despite high satisfaction rates a high percentage of patients take PPIs .