Ovarian reserve is preserved in Behçet's disease

Aim To compare ovarian reserve with anti‐müllerian hormone ( AMH ) levels, antral follicle counts ( AFC s) and ovarian volume in patients with Behçet's disease ( BD ) and healthy subjects. Method This study included 35 women with BD (mean age: 34.4 ± 5.3 years) and 35 healthy controls (mean age: 34.1 ± 6.0 years). Venous blood samples collected from groups on menstrual cycle Days 2–4 were analyzed using the enzyme‐linked immunosorbent assay to measure follicle‐stimulating hormone ( FSH ), luteinizing hormone ( LH ), estradiol (E 2 ), prolactin ( PRL ) and AMH levels. The AFC s and ovarian volumes were estimated by ultrasonography on the same day. The body mass index ( BMI ), duration and severity of the disease, medications, and number of children were recorded. Results There was no statistically significant difference in the mean age, median gravida/para/abortus and the number of live births and mean BMI between the patient and control groups ( P  >   0.05). No statistically significant difference in the median FSH , LH , E2, PRL levels, right and left ovarian volumes, and right and left ovarian AFC s was observed among the patients and the controls ( P  >   0.05). There was no statistically significant difference in the mean AMH levels ( P  =   0.468). Bonferroni correction showed no statistically significant correlation between AMH levels and age, BMI , FSH , LH , E2, PRL levels, right and left ovarian AFC s, right and left ovarian volume ( P  >   0.025) among the controls and the patients. Conclusion Our study results suggest that ovarian reserve is preserved in patients with BD . In addition, AMH levels of the BD patients were similar to levels of healthy subjects.