Open AccessThe sulfur formation system mediating extracellular cysteine‐cystine recycling in Fervidobacterium islandicum AW‐1 is associated with keratin degradation
Author(s) -
Jin HyeonSu,
Dhanasingh Immanuel,
Sung JaeYoon,
La Jae Won,
Lee Yena,
Lee Eun Mi,
Kang Yujin,
Lee Do Yup,
Lee Sung Haeng,
Lee DongWoo
Publication year - 2021
Publication title -
microbial biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.287
H-Index - 74
ISSN - 1751-7915
DOI - 10.1111/1751-7915.13717
Subject(s) - cystine , extracellular , biochemistry , cysteine , chemistry , sulfur , intracellular , sulfur metabolism , biogenesis , redox , proteolysis , keratin , biology , microbiology and biotechnology , metabolism , enzyme , organic chemistry , paleontology , gene
Briefly, our proposed mechanism on keratinolysis associated with the suf operon including the SufSU complex includes three major cellular metabolic pathways; (i) sulfur transfer for Fe‐S cluster biogenesis, (ii) stress response through intracellular cysteine/cystine‐mediated redox homeostasis, and (iii) extracellular cysteine/cystine‐mediated reducing power for sulfitolysis.