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Formation of lithium, sodium and potassium complexes with 1,3,5‐triamino‐1,3,5‐trideoxy‐ cis ‐inositol (taci)
Author(s) -
Neis Christian,
Kradolfer Thomas,
Hegetschweiler Kaspar
Publication year - 2014
Publication title -
acta crystallographica section c
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.304
H-Index - 17
ISSN - 2053-2296
DOI - 10.1107/s2053229614011036
Subject(s) - chemistry , lithium (medication) , crystallography , stereochemistry , potassium , iodide , sodium , aqueous solution , metal , inositol , medicinal chemistry , inorganic chemistry , receptor , organic chemistry , biochemistry , medicine , endocrinology
Single crystals of (1,3‐diamino‐5‐azaniumyl‐1,3,5‐trideoxy‐ cis ‐inositol‐κ 3 O 2 , O 4 , O 6 )(1,3,5‐triamino‐1,3,5‐trideoxy‐ cis ‐inositol‐κ 3 O 2 , O 4 , O 6 )lithium(I) diiodide dihydrate, [Li(C 6 H 16 N 3 O 3 )(C 6 H 15 N 3 O 3 )]I 2 ·2H 2 O or [Li(Htaci)(taci)]I 2 ·2H 2 O (taci is 1,3,5‐triamino‐1,3,5‐trideoxy‐ cis ‐inositol), (I), bis(1,3,5‐triamino‐1,3,5‐trideoxy‐ cis ‐inositol‐κ 3 O 2 , O 4 , O 6 )sodium(I) iodide, [Na(C 6 H 15 N 3 O 3 ) 2 ]I or [Na(taci) 2 ]I, (II), and bis(1,3,5‐triamino‐1,3,5‐trideoxy‐ cis ‐inositol‐κ 3 O 2 , O 4 , O 6 )potassium(I) iodide, [K(C 6 H 15 N 3 O 3 ) 2 ]I or [K(taci) 2 ]I, (III), were grown by diffusion of MeOH into aqueous solutions of the complexes. The structures of the Na and K complexes are isotypic. In all three complexes, the taci ligands adopt a chair conformation with axial hydroxy groups, and the metal cations exhibit exclusive O‐atom coordination. The six O atoms of the resulting M O 6 unit define a centrosymmetric trigonal antiprism with approximate D 3 d symmetry. The interligand O...O distances increase significantly in the order Li < Na < K. The structure of (I) exhibits a complex three‐dimensional network of R —NH 2 —H...NH 2 — R , R —O—H...NH 2 — R and R —O—H...O(H)—H...NH 2 — R hydrogen bonds. The structures of the Na and K complexes consist of a stack of layers, in which each taci ligand is bonded to three neighbours via pairwise O—H...NH 2 interactions between vicinal HO—CH—CH—NH 2 groups.