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A perdeuterated cryoprotectant for neutron studies and a demonstration of its use for neutron powder diffraction on l ‐(−)‐ephedrine hemihydrate
Author(s) -
Krebs Frederik C.,
Jørgensen Mikkel,
Lebech Bente,
Frydenvang Karla
Publication year - 2001
Publication title -
journal of applied crystallography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.429
H-Index - 162
ISSN - 1600-5767
DOI - 10.1107/s0021889800018987
Subject(s) - neutron diffraction , cryoprotectant , chemistry , crystallography , neutron , neutron scattering , powder diffraction , small angle neutron scattering , materials science , crystal structure , nuclear physics , physics , microbiology and biotechnology , embryo , cryopreservation , biology
The use of perdeuteropolyethylpropylene (d‐PEP) as a cryoprotectant for neutron studies of molecular organic solids is demonstrated by the solution of the structure of l ‐(−)‐ephedrine hemihydrate from neutron powder diffraction data on a sample containing 20 wt% d‐PEP. It is demonstrated that no contribution from d‐PEP to the scattering is observed. Neutron diffraction studies of solvent‐containing molecular crystals that require a perdeuterated cryoprotectant oil are thus possible.