The Role of Antibodies and Serum Complement in the Interaction between Macrophages and Leptospires | Zendy

Elena Banfi | Zendy; Marina Cinco | Zendy; Massimo Bellini | Zendy; Maria Rosa Soranzo | Zendy

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The Role of Antibodies and Serum Complement in the Interaction between Macrophages and Leptospires

Author(s) -

Elena Banfi,

Marina Cinco,

Massimo Bellini,

Maria Rosa Soranzo

Publication year - 1982

Publication title -

microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.019

H-Index - 179

eISSN - 1465-2080

pISSN - 1350-0872

DOI - 10.1099/00221287-128-4-813

Subject(s) - phagocytosis , leptospira , microbiology and biotechnology , virulence , antibody , strain (injury) , macrophage , complement (music) , guinea pig , biology , complement system , homologous chromosome , chemistry , immunology , serotype , in vitro , phenotype , biochemistry , genetics , anatomy , complementation , gene

Guinea-pig macrophages exerted bactericidal activity against both a virulent and a saprophytic strain of leptospira in the presence of the homologous IgG. Serum complement alone rendered the saprophytic strain susceptible to phagocytosis by the same macrophages.

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