Open AccessHigh-Accuracy Nodal Staging of Head and Neck Cancer With USPIO-Enhanced MRI
Author(s) -
Daphne A J J Driessen,
Patrik Zámecnik,
Tim Dijkema,
Sjoert Pegge,
Adriana C. H. van Engenvan Grunsven,
Robert P. Takes,
J.H.A.M. Kaanders,
Tom W. J. Scheenen
Publication year - 2022
Publication title -
investigative radiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.33
H-Index - 114
eISSN - 1536-0210
pISSN - 0020-9996
DOI - 10.1097/rli.0000000000000902
Subject(s) - medicine , histopathology , lymph , magnetic resonance imaging , lymph node , radiology , head and neck cancer , neck dissection , cancer , in vivo , pathology , nuclear medicine , carcinoma , radiation therapy , microbiology and biotechnology , biology
Ultrasmall superparamagnetic iron oxide (USPIO)-enhanced magnetic resonance imaging (MRI) is a potential diagnostic tool for lymph node assessment in patients with head and neck cancer. Validation by radiologic-pathologic correlation is essential before the method is evaluated in clinical studies. In this study, MRI signal intensity patterns of lymph nodes are correlated to their histopathology to develop a new USPIO-enhanced MRI reading algorithm that can be used for nodal assessment in head and neck cancer patients.