Open AccessTransmission Cluster of Multiclass Highly Drug-Resistant HIV-1 Among 9 Men Who Have Sex With Men in Seattle/King County, WA, 2005-2007
Author(s) -
Susan E. Buskin,
Giovanina M. Ellis,
Gregory Pepper,
Lisa M. Frenkel,
Steven A. Pergam,
Geoffrey S. Gottlieb,
Carrie Horwitch,
Jeffrey F Olliffe,
Karen Johnson,
Peter Shalit,
Corinne Heinen,
Michael F. Schwartz,
Robert Wood
Publication year - 2008
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e318185727e
Subject(s) - medicine , public health , men who have sex with men , transmission (telecommunications) , cluster (spacecraft) , drug resistance , psychological intervention , outbreak , family medicine , epidemiology , human immunodeficiency virus (hiv) , virology , biology , psychiatry , syphilis , pathology , genetics , computer science , electrical engineering , programming language , engineering
From 2005 through 2007, Seattle health care providers identified cases of primary multiclass drug-resistant (MDR) HIV-1 with common patterns of resistance to antiretrovirals (ARVs). Through surveillance activities and genetic analysis, the local Health Department and the University of Washington identified phylogenetically linked cases among ARV treatment-naive and -experienced individuals.