Open AccessLongitudinal Changes in Sex Hormone–Binding Globulin in Men With HIV
Author(s) -
Jenny Pena Dias,
Sabina A. Haberlen,
Adrian S. Dobs,
Jordan E. Lake,
Frank J. Palella,
Lawrence Kingsley,
Jennifer Price,
Shehzad Basaria,
Ravi Varadhan,
Joseph B. Margolick,
Chloe L. Thio,
Todd T. Brown
Publication year - 2021
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000002723
Subject(s) - sex hormone binding globulin , serostatus , population , medicine , multicenter aids cohort study , endocrinology , globulin , human immunodeficiency virus (hiv) , hormone , immunology , viral load , sida , androgen , viral disease , environmental health
Sex hormone-binding globulin (SHBG) is a glycoprotein that regulates sex hormone bioavailability and increases with age in the general population. SHBG concentrations are higher in people with HIV, a population in whom accelerated aging has been hypothesized. It is unclear whether longitudinal changes in SHBG increase over time and differ by HIV serostatus.