Open AccessIs impaired kidney function an independent predictor of the risk of myocardial infarction in HIV-infected individuals?
Author(s) -
Sylvie Lang,
Murielle MaryKrause,
Marialuisa Partisani,
Jacques Gilquin,
Anne Simon,
Laurent Cotte,
Franck Boccara,
Dominique Costagliola
Publication year - 2014
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000000364
Subject(s) - medicine , odds ratio , kidney disease , myocardial infarction , confidence interval , risk factor , confounding , cardiology , renal function , coronary artery disease , impaired renal function
We examined whether impaired kidney function is an independent risk factor for myocardial infarction in HIV-infected individuals without pre-existing coronary artery disease. The odds ratio for impaired kidney function fell from 1.22 (95% confidence interval 0.90-1.66) to 0.99 (95% confidence interval 0.69-1.41) after adjustment for cardiovascular risk factors and HIV-related parameters, with hypertension, high-density lipoprotein cholesterol, smoking and the CD4 T-cell nadir as most influential confounders. In this setting, no association was found between impaired kidney function and the risk of myocardial infarction.
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