Open AccessA primer on single-cell genomics in myeloid biology
Author(s) -
Kyle Ferchen,
Baobao Song,
H. Leighton Grimes
Publication year - 2020
Publication title -
current opinion in hematology/current opinion in hematology, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.295
H-Index - 97
eISSN - 1080-8213
pISSN - 1065-6251
DOI - 10.1097/moh.0000000000000623
Subject(s) - biology , computational biology , myeloid , stem cell , haematopoiesis , hematopoietic stem cell , progenitor cell , cell , systems biology , bioinformatics , microbiology and biotechnology , immunology , genetics
Understanding the fast-moving field of single-cell technologies, as applied to myeloid biology, requires an appreciation of basic molecular, informatics, and biological concepts. Here, we highlight both key and recent articles to illustrate basic concepts for those new to molecular single-cell analyses in myeloid hematology.