Open AccessA rare acantholytic variant of squamous cell carcinoma of the maxilla
Author(s) -
JoEun Kim,
Chena Lee,
Keunhee Oh,
Kyung-Hoe Huh
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000021631
Subject(s) - medicine , maxilla , malignancy , basal cell , biopsy , incisional biopsy , carcinoma , surgery , dermatology , radiology , pathology , dentistry
Abstract Rationale: Acantholytic squamous cell carcinoma (ASCC) is an uncommon histopathologic variant of squamous cell carcinoma (SCC), which is the most common malignancy of the oral cavity. Though ASCC showed poor prognosis, the exact diagnosis is challenging. Patients concerns: A 59-year-old female patient with 1-month long symptoms of pain and burning sensation in the right maxilla. Diagnoses: Incisional biopsy in the maxilla established the pathologic diagnosis of SCC. Intervention: The patient underwent mass resection with near total maxillectomy. Outcomes: The final diagnosis through the microscopic examination was ASCC. Palliative chemotherapy was done to relive the symptoms after the recurrence, however, the patient died of the disease at 8 months after her initial presentation. Lessons: Special attention should be paid to this variant of SCC because most patients with ASCC have a very poor prognosis.