Open AccessAssociations of high anti-CMV IgG titer with renal function decline and allograft rejection in kidney transplant patients
Author(s) -
Tz-Heng Chen,
ShuoMing Ou,
DerCherng Tarng
Publication year - 2022
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.535
H-Index - 42
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1097/jcma.0000000000000678
Subject(s) - medicine , titer , cytomegalovirus , renal function , immunology , hazard ratio , kidney transplantation , immunoglobulin g , antibody , transplantation , gastroenterology , virus , viral disease , herpesviridae , confidence interval
An anti-cytomegalovirus (CMV) immunoglobulin G (IgG) antibody is produced after primary CMV infection and generally persists after the primary infection. However, it is not well-known about the relationship between anti-CMV IgG titer and outcomes in kidney transplant recipients. We, therefore, aimed to explore the role of anti-CMV IgG titer on the risks of CMV disease development, allograft rejection, renal function decline, and mortality.