Open AccessWITHIN-HOUSEHOLD SHARING OF A FLUOROQUINOLONE-RESISTANT ESCHERICHIA COLI SEQUENCE TYPE ST131 STRAIN CAUSING PEDIATRIC OSTEOARTICULAR INFECTION
Author(s) -
James R. Johnson,
John Anderson,
Connie Clabots,
Brian Johnston,
Michael Cooperstock
Publication year - 2010
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0b013e3181c89bd7
Subject(s) - escherichia coli , medicine , microbiology and biotechnology , osteomyelitis , septic arthritis , strain (injury) , feces , transmission (telecommunications) , enterobacteriaceae , arthritis , immunology , biology , genetics , gene , electrical engineering , engineering
A fluoroquinolone-resistant Escherichia coli strain of sequence type ST131 caused severe septic arthritis and contiguous osteomyelitis in an 8-month-old girl, and colonized the girl's healthy mother, who shared a different fecal E. coli strain with the father. Within-household transmission can contribute to the dissemination of the emerging, multidrug-resistant ST131 clonal group, which has evident invasive potential for otherwise-healthy children.