Open AccessA Congener-specific and Mixture Analysis of Plasma Polychlorinated Biphenyl Levels and Incident Breast Cancer
Author(s) -
Humberto Parada,
Tarik Benmarhnia,
Lawrence S. Engel,
Xuezheng Sun,
ChiuKit Tse,
Eunha Hoh,
Andrew F. Olshan,
Melissa A. Troester
Publication year - 2021
Publication title -
epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.901
H-Index - 173
eISSN - 1531-5487
pISSN - 1044-3983
DOI - 10.1097/ede.0000000000001356
Subject(s) - congener , breast cancer , polychlorinated biphenyl , confidence interval , odds ratio , medicine , logistic regression , demography , cancer , population , oncology , gynecology , chemistry , environmental health , environmental chemistry , sociology
Polychlorinated biphenyls (PCBs), a diverse class of chemicals, are hypothesized mammary carcinogens. We examined plasma levels of 17 PCBs as individual congeners and as a mixture in association with breast cancer using a novel approach based on quantile g-computation.