Open AccessCombined Surgical and Molecular Therapy
Author(s) -
Jason S. Gold,
Ronald P. DeMatteo
Publication year - 2006
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/01.sla.0000218080.94145.cf
Subject(s) - gist , medicine , imatinib mesylate , imatinib , sunitinib , stromal tumor , targeted therapy , tyrosine kinase inhibitor , adjuvant therapy , tyrosine kinase , pdgfra , pathology , interstitial cell of cajal , cancer research , oncology , cancer , stromal cell , immunohistochemistry , receptor , myeloid leukemia
This review describes the pathologic and epidemiologic features of gastrointestinal stromal tumor (GIST) as well as the contemporary management of this tumor. The integration of surgery and treatment with targeted molecular agents in the treatment of GIST is highlighted.