Open AccessCrohn??s Disease Patients Carrying Nod2/CARD15 Gene Variants Have an Increased and Early Need for First Surgery due to Stricturing Disease and Higher Rate of Surgical Recurrence
Author(s) -
Manuel Álvarez-Lobos,
Juan I. Aróstegui,
Miquel Sans,
Dolors Tàssies,
Susana Plaza,
Salvadora Delgado,
Antonio M. Lacy,
Josep M. Piqué,
Jordi Yagüe,
Julián Panés
Publication year - 2005
Publication title -
annals of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.153
H-Index - 309
eISSN - 1528-1140
pISSN - 0003-4932
DOI - 10.1097/01.sla.0000186173.14696.ea
Subject(s) - medicine , odds ratio , nod2 , univariate analysis , crohn's disease , multivariate analysis , genotype , disease , confidence interval , surgery , gastroenterology , gene , genetics , biology
To study the predictive value of Nod2/CARD15 gene variants along with disease phenotypic characteristics for requirement of initial surgery and for surgical recurrence in Crohn's disease (CD).