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Comparison of Diced Cartilage Graft Wrapped in Surgicell and Diced Cartilage Graft Wrapped in Fascia: An Experimental Study
Author(s) -
Coskun Berna Uslu,
Seven Huseyin,
Yigit Ozgur,
Alkan Seyhan,
Savk Hayati,
Basak Tulay,
Dadas Burhan
Publication year - 2005
Publication title -
the laryngoscope
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.181
H-Index - 148
eISSN - 1531-4995
pISSN - 0023-852X
DOI - 10.1097/01.mlg.0000161356.35697.f6
Subject(s) - medicine , cartilage , fascia , resorption , fibrosis , subcutaneous tissue , anatomy , surgery , pathology
Hypothesis: This study was conducted to compare diced cartilage grafts wrapped in fascia and diced cartilage grafts wrapped in surgicell with respect to their resorption. Study Design: Experimental study. Methods: Eight male Wistar Albino rats were used. After general anesthesia, two different subcutaneous pockets (upper and lower pocket) were prepared in the rat's abdomen. Surgicell‐wrapped homograft that was taken from the ear was placed into the upper subcutaneous pocket. Fascia‐wrapped homograft which was taken from the ear was placed into the lower subcutaneous pocket. All the rats were killed at the end of 2 months, and the samples were collected to be examined histopathologically. Cartilage mass, foreign body reaction, fibrosis, chronic inflammation, and vascularization were researched. Results: Diced cartilage wrapped surgicell stained negative for glial fibrillary acidic protein (GFAP). Diced cartilage wrapped in fascia stained positive for GFAP. There was a significant difference between two groups with respect to fibrosis, chronic inflammation, and cartilage mass. There was no significant difference between the two groups regarding vascularization. Conclusions: This study suggests that diced cartilage graft wrapped in surgicell was absorbed, whereas diced cartilage graft wrapped in fascia was not.