Open AccessP1560: IMR‐261, A NOVEL, ORAL NRF2 ACTIVATOR, REDUCES IRON OVERLOAD IN AN EXPERIMENTAL MOUSE MODEL BY ACTIVATING BMP6‐MEDIATED HEPCIDIN SYNTHESIS
Author(s) -
Trovati Maciel T.,
Carvalho C.,
Rignault R.,
Slimane A.,
Drakesmith H.,
Isler OCain J.,
Ballal R.
Publication year - 2022
Publication title -
hemasphere
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 11
ISSN - 2572-9241
DOI - 10.1097/01.hs9.0000849096.76572.19
Subject(s) - hepcidin , ferroportin , hamp , bone morphogenetic protein 6 , transferrin saturation , medicine , erythropoiesis , endocrinology , serum iron , chemistry , hemoglobin , biology , anemia , biochemistry , iron deficiency , bone morphogenetic protein , bone morphogenetic protein 7 , gene