Open AccessComparative potency of three antiretroviral therapy regimes in primary HIV infection
Author(s) -
Sarah Fidler,
Christophe Fraser,
Julie Fox,
Norbert Tamm,
James T. Griffin,
Jonathan Weber
Publication year - 2006
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/01.aids.0000200530.71737.75
Subject(s) - regimen , viral load , medicine , antibody , clinical endpoint , immunology , prospective cohort study , protease inhibitor (pharmacology) , human immunodeficiency virus (hiv) , drug holiday , antiretroviral therapy , cohort , virology , gastroenterology , randomized controlled trial
Virally mediated destruction of HIV-specific CD4+ T-cells in primary HIV infection (PHI) may be abrogated by potent antiretroviral therapy (ART) started in acute infection. To best achieve the most rapid reduction in primary viraemia we compared three different ART regimens in PHI.