Open AccessNovel Genetic Risk Variants Can Predict Anti-TNF Agent Response in Patients With Inflammatory Bowel Disease
Author(s) -
MingHsi Wang,
Jessica J. Friton,
Laura E. Raffals,
Jonathan A. Leighton,
Shabana F. Pasha,
M.F. Picco,
Kelly C. Cushing,
Kelly Monroe,
Billy D. Nix,
Rodney D. Newberry,
William A. Faubion
Publication year - 2019
Publication title -
journal of crohn's and colitis
Language(s) - English
Resource type - Journals
eISSN - 1876-4479
pISSN - 1873-9946
DOI - 10.1093/ecco-jcc/jjz017
Subject(s) - medicine , inflammatory bowel disease , odds ratio , disease
It is important to identify patients with inflammatory bowel disease [IBD] refractory to anti-tumour necrosis factor [TNF] therapy, to avoid potential adverse effects and to adopt different treatment strategies. We aimed to identify and validate clinical and genetic factors to predict anti-TNF response in patients with IBD.