Genetic polymorphisms in the surfactant proteins in systemic sclerosis in Japanese: T/T genotype at 1580 C/T (Thr131Ile) in the SP-B gene reduces the risk of interstitial lung disease
Author(s) -
Yoshiko Sumita,
Tomoko Sugiura,
Yasushi Kawaguchi,
S. Baba,
Makoto Soejima,
Yohko Murakawa,
Masahiko Hara,
Naoyuki Kamatani
Publication year - 2007
Publication title -
lara d. veeken
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.957
H-Index - 173
eISSN - 1462-0332
pISSN - 1462-0324
DOI - 10.1093/rheumatology/kem355
Subject(s) - genotype , single nucleotide polymorphism , interstitial lung disease , medicine , snp , gastroenterology , genotype frequency , gene polymorphism , immunology , gene , lung , microbiology and biotechnology , genetics , biology
To investigate the association between single-nucleotide polymorphisms (SNPs) in the pulmonary surfactant protein (SP) genes and the presence or absence of interstitial lung disease (ILD) in SSc patients.
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