In vitro activity of temocillin against extended spectrum β-lactamase-producing Escherichia coli | Zendy

Hector Rodríguez-Villalobos | Zendy; Vincent Malaviolle | Zendy; Joëlle Frankard | Zendy; Ricardo De Mendonça | Zendy; Claire hoff | Zendy; Marc Struelens | Zendy

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In vitro activity of temocillin against extended spectrum β-lactamase-producing Escherichia coli

Author(s) -

Hector Rodríguez-Villalobos,

Vincent Malaviolle,

Joëlle Frankard,

Ricardo De Mendonça,

Claire hoff,

Marc Struelens

Publication year - 2006

Publication title -

the journal of antimicrobial chemotherapy/journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkl046

Subject(s) - microbiology and biotechnology , ticarcillin , cefepime , ceftazidime , meropenem , piperacillin , imipenem , ciprofloxacin , cefotaxime , biology , amikacin , tazobactam , tobramycin , gentamicin , agar dilution , escherichia coli , antimicrobial , antibiotics , antibiotic resistance , minimum inhibitory concentration , bacteria , pseudomonas aeruginosa , biochemistry , genetics , gene

Temocillin is a semi-synthetic 6-alpha-methoxy derivative of ticarcillin. It is highly stable to most bacterial beta-lactamases. However, data concerning its activity against extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae are limited. We have analysed the in vitro activity of temocillin against clinical isolates of ESBL-producing Escherichia coli over the past 4 years in a university hospital in Brussels, Belgium.

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