Open AccessEvolutionary simulations to detect functional lineage-specific genes
Author(s) -
Isabelle Dupanloup,
Henrik Kaessmann
Publication year - 2006
Publication title -
bioinformatics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.599
H-Index - 390
eISSN - 1367-4811
pISSN - 1367-4803
DOI - 10.1093/bioinformatics/btl280
Subject(s) - lineage (genetic) , biology , gene , inference , computational biology , selection (genetic algorithm) , statistical inference , constraint (computer aided design) , similarity (geometry) , genetics , coding region , evolutionary biology , computer science , artificial intelligence , mathematics , statistics , geometry , image (mathematics)
Supporting the functionality of recent duplicate gene copies is usually difficult, owing to high sequence similarity between duplicate counterparts and shallow phylogenies, which hamper both the statistical and experimental inference.
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