Open AccessThe Role of Processing Speed in Post-Stroke Cognitive Dysfunction
Author(s) -
C Y Su,
YeePay Wuang,
Y.H. Lin,
J.-H. Su
Publication year - 2015
Publication title -
archives of clinical neuropsychology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 98
eISSN - 1873-5843
pISSN - 0887-6177
DOI - 10.1093/arclin/acu057
Subject(s) - cognition , neurocognitive , stroke (engine) , cognitive flexibility , neuropsychology , psychology , verbal memory , audiology , neuropsychological test , effects of sleep deprivation on cognitive performance , visual memory , working memory , medicine , neuroscience , mechanical engineering , engineering
The association between speed of information processing and cognition has been extensively validated in normal aging and other neurocognitive disorders. Our aim was to determine whether such a relationship exists in stroke. Thirty patients and 30 age- and education-matched healthy individuals were administered a comprehensive battery of neuropsychological tests divided into the following six cognitive domains: processing speed (PS), verbal memory, visual memory, visuoperceptual function, language, and cognitive flexibility. The results demonstrate that stroke patients were characterized by cognitive deficits in almost all of these domains, but have the most pronounced deficits in PS. After adjusting for symbol digit modalities test score, all significant group differences in cognitive functioning disappeared. However, group differences remained significant after controlling for the influence of other cognitive factors. These findings suggest that decreased PS appears to underlie post-stroke cognitive dysfunction and may serve as a potential target for intervention.
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