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Docosahexaenoic acid supplementation failed to attenuate chronic alcoholic fatty liver in mice
Author(s) -
Yi Wang,
Yuying Zhao,
Mingzhuo Li,
Yunxuan Wang,
Shuqing Yu,
Tao Zeng
Publication year - 2016
Publication title -
acta biochimica et biophysica sinica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.771
H-Index - 57
eISSN - 1745-7270
pISSN - 1672-9145
DOI - 10.1093/abbs/gmw016
Subject(s) - docosahexaenoic acid , fatty liver , chronic alcoholic , medicine , endocrinology , chemistry , fatty acid , biochemistry , polyunsaturated fatty acid , disease
The roles of n-3 polyunsaturated fatty acids (PUFAs) including docosahexaenoic acid (DHA) in alcoholic fatty liver (AFL) have been investigated in a series of studies. DHA andDHA-rich fish oil were found to provide protection against acute AFL [1,2], while their effects on chronic AFL is still a controversial issue. Although Song et al. [3] found that DHA and arachidonic acid prevented chronic AFL, several

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