Open AccessThe effect of polyazolidinammonium on the dynamics of the synthesis of pseudotuberculosis antibodies
Author(s) -
С. В. Иващенко,
В. С. Кузнецова,
S. V. Savina,
V. M. Skorlyakov
Publication year - 2020
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/421/2/022055
Subject(s) - yersinia pseudotuberculosis , titer , adjuvant , antibody , chemistry , subcutaneous injection , connective tissue , biology , medicine , immunology , pathology , biochemistry , virulence , gene
The use of a 1% solution of polyazolidin-ammonium modified with iodine hydrate ions (PAAG) in combination with disintegrated Yersinia pseudotuberculosis membranes made it possible to obtain hyperimmune serum with a high content of antibodies and species specificity. By the number of antibodies and the growth dynamics of their titers, PAAG was not inferior to Freund’s complete adjuvant. At the sites of injection of PAAG, connective tissue densification of the subcutaneous tissue was not observed.