Open AccessDo Sex and Race/Ethnicity Influence CD4 Cell Response in Patients Who Achieve Virologic Suppression during Antiretroviral Therapy?
Author(s) -
Thomas P. Giordano,
John A. Wright,
Mehedi Hasan,
A. Clinton White,
Edward A. Graviss,
Fehmida Visnegarwala
Publication year - 2003
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/376638
Subject(s) - medicine , regimen , multivariate analysis , antiretroviral therapy , protease inhibitor (pharmacology) , sida , univariate analysis , ethnic group , cohort , univariate , observational study , immunology , cohort study , viral load , human immunodeficiency virus (hiv) , viral disease , multivariate statistics , sociology , mathematics , anthropology , statistics
To determine whether CD4 cell count response to virus suppression during highly active antiretroviral therapy differs according to sex or race/ethnicity, we analyzed data in our observational cohort study for patients receiving their first antiretroviral regimen who experienced virus suppression by 6 months of therapy. In both univariate and multivariate analyses, women had greater CD4 cell count increases, compared with men, as did patients receiving a regimen that did not include a protease inhibitor. Race/ethnicity was not a factor.
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