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Amplification of xenon NMR and MRI by remote detection
Author(s) -
Adam J. Moulé,
Megan M. Spence,
Songi Han,
Juliette A. Seeley,
Kimberly L. Pierce,
Sunil Saxena,
Alexander Pines
Publication year - 2003
Publication title -
proceedings of the national academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.011
H-Index - 771
eISSN - 1091-6490
pISSN - 0027-8424
DOI - 10.1073/pnas.1133497100
Subject(s) - electromagnetic coil , magnet , xenon , polarization (electrochemistry) , nuclear magnetic resonance , excitation , interference (communication) , magnetic field , radiofrequency coil , materials science , physics , computational physics , computer science , chemistry , atomic physics , telecommunications , channel (broadcasting) , quantum mechanics
A technique is proposed in which an NMR spectrum or MRI is encoded and stored as spin polarization and is then moved to a different physical location to be detected. Remote detection allows the separate optimization of the encoding and detection steps, permitting the independent choice of experimental conditions and excitation and detection methodologies. In the initial experimental demonstration of this technique, we show that taking dilute 129Xe from a porous sample placed inside a large encoding coil and concentrating it into a smaller detection coil can amplify NMR signal. In general, the study of NMR active molecules at low concentration that have low physical filling factor is facilitated by remote detection. In the second experimental demonstration, MRI information encoded in a very low-field magnet (4-7 mT) is transferred to a high-field magnet (4.2 T) to be detected under optimized conditions. Furthermore, remote detection allows the utilization of ultrasensitive optical or superconducting quantum interference device detection techniques, which broadens the horizon of NMR experimentation.

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