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Daratumumab plus Lenalidomide and Dexamethasone for Untreated Myeloma
Author(s) -
Thierry Façon,
Shaji Kumar,
Torben Plesner,
Robert Z. Orlowski,
Philippe Moreau,
Nizar J. Bahlis,
Supratik Basu,
Hareth Nahi,
Cyrille Hulin,
Hang Quach,
Hartmut Goldschmidt,
Michael O’Dwyer,
Aurore Perrot,
Christopher P. Venner,
Katja Weisel,
Joseph R. Mace,
Noopur Raje,
Michel Attal,
Mourad Tiab,
Margaret Macro,
Laurent Frenzel,
Xavier Leleu,
Tahamtan Ahmadi,
Christopher Chiu,
Jianping Wang,
Rian Van Rampelbergh,
Clarissa Uhlar,
Rachel Kobos,
Ming Qi,
Saad Z. Usmani
Publication year - 2019
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1817249
Subject(s) - daratumumab , lenalidomide , dexamethasone , multiple myeloma , medicine , oncology
Lenalidomide plus dexamethasone is a standard treatment for patients with newly diagnosed multiple myeloma who are ineligible for autologous stem-cell transplantation. We sought to determine whether the addition of daratumumab would significantly reduce the risk of disease progression or death in this population.

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