Open AccessPlatelet-Rich Plasma: Principles and Applications in Plastic Surgery
Author(s) -
Amjed AbuGhname,
Aurelia Trisliana Perdanasari,
Matthew J. Davis,
Edward M. Reece
Publication year - 2019
Publication title -
seminars in plastic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.5
H-Index - 25
eISSN - 1536-0067
pISSN - 1535-2188
DOI - 10.1055/s-0039-1693400
Subject(s) - platelet rich plasma , medicine , platelet , plastic surgery , rejuvenation , platelet concentrate , clinical practice , surgery , reconstructive surgery , wound healing , family medicine
Platelet-rich plasma (PRP) is an autogenously harvested liquid platelet concentrate extracted from a patient's peripheral blood that contains higher than baseline concentrations of growth factors and cytokines. This innovative new technology has demonstrated great promise in the field of plastic surgery, and its use has been evaluated in several clinical settings including wound healing, hair restoration, and skin rejuvenation. The goal of this article is to explain the biology behind PRP and to review the basic principles involved in its preparation. This will be followed by a discussion of some clinical applications of PRP in both aesthetic and reconstructive plastic surgery.